| Cat. No. | Volume | |
| Nanofectin siRNA | Q0002-007 | 200 µl |
| Q001-007 | 1.0 ml |
General
The inhibition of genes respectively of the corresponding mRNA (Gene silencing) is an important tool for the study of the gene functions in cells. In the past several strategies such as the use of anti-sense oligonucleotides, ribozymes, aptameres and, more recently, small interference RNA (siRNA) were developed to inhibit mRNA translation which results in an inhibition of the gene expression. Only special transfection reagents form stable transfection complexes which can directly and efficiently bring siRNA into animal cells to induce gene silencing.
Nanotechnology in Gene Silencing
Nanofectin siRNA is a new transfection reagent for efficient binding, protection and transfer of silencing RNA into mammalian cells. The unique structure of nanoparticles and the small positively charged carrier molecules optimized for binding of siRNA guarantee highest protection. Transfection of the siRNA complex into the cells proved to provide more than 85% efficiency on target gene expression in different cell lines.
Applications
- Transfection reagent for mammalian cells
- Transfection of siRNA
- Gene silencing
- siRNA-DNA co-transfection
- Broad cell range reagent
Features
- Efficient siRNA transfection
- With low siRNA concentration
- Over 85% gene silencing
- Highly reproducible
- Tested on many different cell types
- Transfection in the presence or absence of serum
- Excellent cell viability
- Non toxic
- Easy standard protocol for use
Product Specifications
| Solvent | Water |
| Diluent | PBS, serum free media |
| Cell Culture | tested |
| Sterility | tested |
| Shelf Life | 2 years |
| Storage | ≤-15°C |