| Cat. No. | Volume | |
| Human Serum, off the clot | ||
| Type AB | C11-021 | 100 ml |
| C15-021 | 500 ml |
General
Human serum contains high concentrations of growth factors. Therefore human serum is an optimal supplement in nutrient media for in vitro growth of different primary-, tumour- and stem cells.
Human Serum - the ideal Growth Supplement
Human embryonic stem cells (hESC) can potentially differentiate into every body cell type, making them ideal candidates for cell- and tissue-replacement therapies. Human ES cells are normally cultured with animal derived sera in combination with an animal feeder layer. Recently it was found that hES cells express an immunogenic non-human sialic acid against which many humans have circulating antibodies when cultured with animal derived growth supplements. Therefore hES cells grown in animal derived components cannot be re-implanted into patients because allergic reactions will be induced and the hES cells will be rejected.
Human Serum with no allergenic Potential
In order to avoid immunogenic reactions human serum must be used in combination with human feeder layers. Only hES cells grown in non animal derived components can be re-implanted into patients.
PAA's Human Serum with highest Safety
The collection of raw serum is undertaken in FDA controlled plasmapheresis centers. The collected raw serum is taken strictly from donors that have been under medical control for a minimum of six months. Each single donor unit taken is subjected to extensive tests such as absence of HIV1 and 2, HIV-1Ag, anti-HCV and HbsAg.
Features
- Special serum batches
- Low endotoxin content
- Tested for human viruses and antibodies
- Tested for microorganisms
- No allergenic potential
- No formation of sialic acid residues
- For re-implantation experiments
- For growth and maintenance of human embryonic stem cells
Optional: For highest virus safety human serum can be gamma sterilized.