Cat. No.	Volume
G-418 Sulphate	P21-011	1 g
	P25-011	5 g
	P31-011	10 g
G-418 Sulphate Solution (50 mg/ml)	P02-012	20 ml
	P11-012	100 ml

G-418 is an aminoglycoside antibiotic that interferes with the function of 80S ribosomes in protein synthesis in eukaryotic and prokaryotic cells. G-418 blocks polypeptide synthesis by binding irreversibly to 80S ribosomes and inhibiting the elongation step. It is used as a selective antibiotic in molecular and cell biology. G-418 is usually more effective in multiplying cells than in those which are not dividing. A multiplying cell will require 3 to 7 days for death to occur.

• Selection antibiotic
• Neomycin transferase inactivates G-418
• Transfections with the neomycin gene are resistant to G-418
• Transient and stable transfection

• Antibiotic with a broad spectrum of activity
• Toxic against all prokaryotes and eukaryotes
• High purity
• High activity
• Packed in dark glass bottles
• Sterile solution

Recommended final concentration: 100 µg/ml – 1mg/ml

Activity (Powder)	> 600 µg/mg
Endotoxin	< 10 EU/ml
Shelf Life	2 years
Storage (Powder)	+15°C to +25°C
Storage (Solution)	+2 to +8°C