Cat. No. Volume
Amphotericin B P11-001 100 ml

General

Amphotericin B is an antifungal agent that is used in tissue culture for the control of yeasts and fungi. It acts by binding to steroidal alcohols in the cell membrane of susceptible fungi. Amphotericin B creates channels in the cell membrane resulting in an increase of membrane permeability. The loss of cations through the channels into the extracellular space and the inhibition of a number of membrane bound enzymes destroy the yeast or fungus. Amphotericin B has no effect on bacteria and viruses.

Applications

  • Antifungal spectrum
  • Interacts with membranes of fungi
  • Forms channels in membranes

Working Concentration

Recommended final concentration: 10 ml/l

Product Specifications

pH 6.5 – 8.0
Osmolality 0 – 50 mOsmol/kg
Endotoxin < 10 EU/ml
Cell Culture tested
Sterility tested
Shelf Life 2 years
Storage ≤ -15°C
Stability 5 days at +37°C

Formulation

Amphotericin B 0.25 mg/ml
Solvent Water